Neuropeptide B/W Receptor
Neuropeptide B and W (NPB and NPW) have been identified as endogenous ligands of two G-protein-coupled receptors, neuropeptides B/W receptor 1 (NPBWR1, formerly known as GPR7) and neuropeptides B/W receptor 2 (NPBWR2, formerly known as GPR8). Both neuropeptides B and W take a part in the central regulation of neuroendocrine axes, feeding behavior, energy homeostasis, cardiovascular functions, circadian rhythm, pain sensation, modulation of inflammatory pain, and emotions.
All Product Categories
-
Neuropeptide B/W Receptor Related Products (9)
Related Products (9)
-
Neuropeptide W-23 (human)
0 ImagesSynonyms: NPW-23Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8).
-
CYM 50769
0 ImagesCYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation.
-
Neuropeptide W-30 (rat) acetate
0 ImagesCat. No.: HY-P10289ASynonyms: NPW30, rat acetateNeuropeptide W-30 (rat) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (rat) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. NPW-30 activates and binds to both GPR7 and GPR8 at similar effective doses.
-
Biotinyl-neuropeptide W-23 (human)
0 ImagesBiotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8).
-
(Des-Bromo)-Neuropeptide B (1-23) (human)
0 ImagesCat. No.: HY-P4414CAS No.: 434897-64-0(Des-Bromo)-Neuropeptide B (1-23) (human) is an orphan G-protein coupled receptor agonist with Kis of 1.2 nM and 341 nM for GPR7 (NPBW1) and GPR8 (NPBW2), respectively.
-
Neuropeptide W-30 (human)
0 ImagesCat. No.: HY-P10287CAS No.: 383415-80-3Synonyms: NPW30, humanNeuropeptide W-30 (human) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (human) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. Neuropeptide W-30 (human) activates and binds to both GPR7 and GPR8 at similar effective doses.
-
Neuropeptide W-30 (rat)
0 ImagesCat. No.: HY-P10289CAS No.: 383415-90-5Synonyms: NPW30, ratNeuropeptide W-30 (rat) is an important stress mediator in the central nervous system that modulates the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. Neuropeptide W-30 (rat) is an endogenous ligand for the two structurally related orphan G-protein-coupled receptors (GPCRs) GPR7 and GPR8. NPW-30 activates and binds to both GPR7 and GPR8 at similar effective doses.
-
CYM 50769 (Standard)
0 ImagesCat. No.: HY-108624RCAS No.: 1421365-63-0CYM 50769 (Standard) is the analytical standard of CYM 50769 (HY-108624). This product is intended for research and analytical applications. CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation.
